Wednesday, 12 October 2011

Olanzapine - Wikipedia, the free encyclopedia

Use in elderly

Citing an increased risk of stroke, in 2004 the Committee on the Safety of Medicines (CSM) in the UK issued a warning that olanzapine and risperidone, both atypical antipsychotic medications, should not be given to elderly patients with dementia. In the U.S., olanzapine comes with a black box warning for increased risk of death in elderly patients. It is not approved for use in patients with dementia-related psychosis.[18] However, a BBC investigation in June 2008 found that this advice was being widely ignored by British doctors.[19]